A case of myxoedema coma successfully treated with tri-iodo-thyronine.

Introduction The termination of myxoedema in coma was described in the Report of the Clinical Society of London(i888) and had been noted even before this (St. Thomas's Hospital Report, I879). It is an uncommon complication occurring in longstanding untreated cases and hitherto was fatal, with the possible exception of one patient (Malden, 1955), and here the cerebro-spinal fluid protein was markedly raised and on recovery there was a unilateral hypereflexia suggesting a cerebrovascular accident complicating myxoedema. This article reports the successful treatment of an undoubted case of myxoedema coma with oral tri-iodo-thyronine.